Скачать или смотреть Diffuse Large B-Cell Lymphoma | Part I: Epidemiology, Genetics, Subtypes, Workup, and Pathology

Diffuse large b-cell lymphoma is the most common form of non-Hodgkin's lymphoma, which ranks 6th in both men and women when it comes to cancer incidence and mortality (excluding prostate and breast cancer). This can seem like a daunting disease for the medical student or resident to understand, but I try and break it down into manageable pieces here. This video explains the subtypes of DLBCL, including germinal center b-cell type vs activated b-cell type, the basic molecular biology and genetics, including the myc, bcl-2, and bcl-6 genes, and the workup needed to diagnose diffuse large b-cell lymphoma.

This video is intended to be at the level of a internal medicine resident.

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#lymphoma #cancertherapy #moleculargenetics #hematology #oncology

00:00 Intro
00:39 Epidemiology
01:55 Molecular Biology and Genetics
05:03 Subtypes
16:18 CNS DLBCL
20:23 Workup and Pathology
25:52 Outro

References:
https://jhoonline.biomedcentral.com/a...
https://www.cell.com/cell/fulltext/S1...
https://pmc.ncbi.nlm.nih.gov/articles...
https://www.sciencedirect.com/science...
https://pmc.ncbi.nlm.nih.gov/articles...
https://www.nejm.org/doi/10.1056/NEJM...
https://acsjournals.onlinelibrary.wil...
https://pmc.ncbi.nlm.nih.gov/articles...
https://radiopaedia.org/articles/lymp...
https://ascopubs.org/doi/10.1200/JCO....
https://www.sciencedirect.com/science...
https://www.nature.com/articles/bjc20...
https://www.pathologyoutlines.com/top...
https://link.springer.com/article/10....
https://metasystems-probes.com/en/pro...