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🍎 Vitamin B3 Deficiency (Pellagra) EXPLAINED: Pathogenesis, Clinical Features & Treatment (USMLE High-Yield Beginner’s Guide)
Ever wondered how a deficiency in Vitamin B3 (niacin) leads to pellagra? In this video, we break down the pathogenesis, clinical signs, and treatment strategies for pellagra—a condition characterized by the “3 D’s”: Dermatitis, Diarrhea, and Dementia. Perfect for medical students, USMLE prep, and healthcare professionals interested in nutritional deficiencies and high-yield exam topics!

What You’ll Learn in This Video:
✔️ Pathogenesis:
How Vitamin B3 deficiency disrupts cellular metabolism
The biochemical pathways affected, including NAD⁺/NADP⁺ synthesis
✔️ Clinical Features:
The classic “3 D’s”: Dermatitis, Diarrhea, and Dementia
Additional signs like glossitis and photosensitive dermatitis
✔️ Diagnosis & Differential Diagnosis:
Key lab findings and clinical tests to confirm pellagra
How to differentiate from other nutritional deficiencies
✔️ Treatment Strategies:
Niacin supplementation and dietary modifications
Management of complications and supportive care
✔️ USMLE High-Yield Pearls:
Mnemonics and exam tips for remembering key facts about pellagra


💬 Question for You:
Which aspect of pellagra do you find most challenging to remember: the clinical features, the pathogenesis, or the treatment strategies? Let us know in the comments below! 😊

👍 Help Us Grow:
Like this video if you found it helpful
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⚠️ Disclaimer:
This video is intended for educational purposes only and does not replace professional medical advice. Always consult a healthcare provider for diagnosis and treatment.

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