Скачать или смотреть EXONS, ISOFORMS, AND THE ARCHITECTURE OF LIFE

The link to the original paper:
https://doi.org/10.1186/s13059-025-03...

Key-words: Protein structure, alternative splicing, AlphaFold2, isoform function, single-cell RNA-seq, splice variants, structural similarity, sequence identity, template matching score, secondary structure, surface charge, radius of gyration, post-translational modification, structure-based function prediction, exon skipping, alternative last exon, alternative first exon, intron retention, mutually exclusive exons, intrinsically disordered regions, solvent accessibility, gene ontology, multiple sequence alignments, pLDDT, Protein Data Bank, root mean squared deviation, phosphorylation, kinases, apoptosis, cell types, Tabula Sapiens, COFACTOR, UniProt, SwissProt, CHESS database, eukaryotic cells, protein compactness, loss of function, pre-mRNA, subcellular localization, ColabFold, cellular resolution, isolated helices, contact map, immune response, ribosome biogenesis, protein diversity, transcriptomes, regression analysis, proteome.