Acute Intermittent Porphyria - Disorders of Heme Synthesis - Biochemistry & Hematology

Acute Intermittent Porphyria (AIP) is a genetic disorders of Heme Synthesis pathway (Heme Metabolism)…It’s caused by deficiency of the enzyme porphoibilinogen deaminase | Biochemistry & Hematology…Repeated attacks of acute, severe abdominal pain, neuropsychiatric symptoms (psychosis, dementia, hallucinations, anxiety)…peripheral neuropathy, purple-colored urine (red-tinged urine that gets oxidized upon exposure to light or air, elevated levels of porphobilinogen, aminolevulenic acid (ALA), and porphyrines..There is no photosensitivity…Treatment includes glucose and hemin (a heme analogue)…What are the different types of porphyria?…Porphyria cutanea tarda vs acute intermittent porphyria.
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