Neuropathic pain - explaining the mechanisms

The Neurobiology of Pain and Neuropathic Pain
0:00 introduction
1:30 what is pain
5:35 Nociception and pain perception
7:26 explanation of terms (neuropathic pain and itch
9:39 Nociceptors
12:19 Nociception
14:36 Peripheral hypersensitivity
15:05 - Nociception - transmission
16:27 Transmission Wind up
23:00 non neuronal "neuropathic" pain
26:20 Monoclonal antibody targeting NGF #solensia #librella
28:09 Modulation of pain
29:55 Corticolimbic Circuitry (pain matrix) and maladaptive pain
37:29 Summary and Conclusions

🧠🌡️ This video explores the intriguing world of pain perception and nociception with a particular focus on management of Neuropathic Pain. Join me on a journey through the neural pathways from nociceptor to the corticolimbic system and unravel the mechanisms that shape an experience of pain.
🔬 We'll delve into the world of neuropathic pain – a condition that arises from faulty nerve signalling giving rise to an array of unique sensations like burning, tingling, and electric shocks.
💊 Gain insights into potential pharmaceutical approaches for addressing neuropathic pain. Moreover, explore the intriguing connection between neuropathic pain and behavioural problems in animals, shedding light on the complexities faced by veterinary surgeons, veterinary nurses, physiotherapists, and specialists in emotional health and behaviour.
💡 This video isn't just limited to veterinary circles; it offers valuable insights to a broader audience. Whether you're a professional caring for animals with chronic pain or an owner seeking a better understanding of the medications your beloved companion receives, this video provides a comprehensive overview. Remember, while our focus is on companion animals, the principles of neurobiology and neuropathic pain transcend species boundaries, touching the lives of humans and various other disciplines as well.
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🔔 Don't miss this captivating exploration of pain's inner workings – from neural pathways to improved management. Like, comment, share, and subscribe to stay engaged with our thought-provoking content. Join us in expanding our understanding of pain's intricacies across species boundaries! 🌍🧬🌟

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