Role of Depression and Antidepressants on Pain

During the April 2021 Pain Science Lecture Series, Theresa Lii, MD presents a lecture on the role of depression and antidepressants on Pain.

The Pain Science Lecture Series was created in 2016 by Heather Poupore-King, PhD, a Stanford clinical associate professor in the division of pain medicine and pain psychologist, to provide community-based education about chronic pain. These free monthly series are presented by Stanford pain medicine and pain psychology fellows and focus on various topics, including biological, psychological, behavioral and social factors as they relate to the experience of chronic pain.

Stanford Division of Pain Medicine
https://med.stanford.edu/pain.html

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0:00 Introduction
0:34 What is Pain?
1:36 The Nervous System
2:18 How Pain Travels to the Brain
5:18 Types of Pain Nociceptive vs Neuropathic Pain
7:16 Why Antidepressants?
7:56 Major Depression
8:15 Which Came First?
8:45 What Predicts Future Pain?
10:50 Evidence for Antidepressants
11:42 How Do Antidepressants Work for Chronic Pain?
13:11 Where Do Antidepressants Act?
14:27 What is Pain Modulation?
15:03 Types of Antidepressants Used for Chronic Pain
16:26 Side Effects of Tricyclics
17:40 Duloxetine (Cymbalta)
18:47 Let's Talk About Pain Psychology
19:02 Pain Psychology Can Help!
19:38 Breaking the Chronic Pain Cycle
21:27 What Can Pain Psychology Offer
22:41 How to Beat Chronic Pain!
23:31 References