The Science behind Spironolactone | Dr Davin Lim

Big thankyou to my colleague, Eshini, for helping me out with this video!
Find her on instagram - @dr.esh.perera

What is the science behind spironolactone?

Spironolactone is an anti-male hormone (anti-androgen) medication. It blocks the male hormone receptor and reduces the level of the male hormones, testosterone and DHEAS. This tablet was first used as a diuretic (“fluid tablet”) effect and increases urine production. This medication lowers blood pressure and reduces fluid retention.

Spironolactone is an oral medication & not a cream because androgens (the target for spironolactone) is found circulating in the bloodstream.
.
.
What skin conditions can be treated with spironolactone?

Hormonal acne: It’s the impact spironolactone has on the hormones that give it its acne fighting reputation. That’s because it blocks the effect that androgens have on oil glands. This medication is an alternative to Accutane or Oratane.

Hair loss in women: Due to its impact on hormone regulation, the drug has recently been prescribed for women experiencing hair loss, also known as androgenic alopecia.

Excessive unwanted hair: On the other hand excessive hair known as hirsutism, commonly seen in PCOS can be treated with spironolactone.

Oily skin: can also be effectively treated with this medication. Most patients only require a very small dose of between 50 to 75 mg.

To see if you are a good candidate for this medication, book in with one of the medical dermatologists @cutis_dermatology.

*Disclaimer: I am a procedural dermatologist, I do not treat medical conditions such as hair loss, acne or other conditions that require prescriptions/tablets.