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While many recent studies demonstrate that space environments affect genes involved in key cellular processes, Dr Borg’s study focuses on the activation of blood production, with hemoglobin serving as a prime example, in spaceflight studies. Using multi-omic data from space missions including the NASA Twins Study, Inspiration4 (i4) data, the JAXA Cell-Free Epigenome (CFE) study, and datasets from the Open Science Data Repository, Prof Borg and team examined how hemoglobin gene expression changes over time and in different space conditions. The findings revealed significant variations in gene expression, offering valuable insights into how the space environment influences biological processes.

Link to Publication: https://www.nature.com/articles/s4146...

Links to Datasets:
OSD-530: https://osdr.nasa.gov/bio/repo/data/s...
OSD-570: https://osdr.nasa.gov/bio/repo/data/s...

Learn more about Analysis Working Groups (AWGs): https://www.nasa.gov/osdr-working-gro...

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