Скачать или смотреть How does HYLO-DUAL® work?

HYLO-DUAL® eye drops contain Sodium Hyaluronate (like in HYLO®) and Ectoine.

Ectoine, is a natural substance formed by microorganisms to protect themselves from extreme environments (e.g.: salt lakes or hot geysers). They adapt to these conditions by so-called extremolytes. Extremolytes like Ectoine are osmoprotective substances, which stabilize biological membranes.

Ectoine has a strong water-binding capacity. The water surrounding Ectoine is bound very compact, and forms a physiologic barrier. This “shield” of Ectoine and water protects cell membranes from contact with allergenic substances and against inflammatory responses to environmental stress (such as dehydration, e.g. by hyperosmolar tears, UV radiation or airborne allergens). Additionally, Ectoine has a stabilizing effect on the lipid phase of the tear film. It increases its elasticity, causes it to spread evenly over the eye surface, and protects against the excessive evaporation of tears.

Burning, itching, tearing, foreign body sensation can be caused by insufficient moisture or by hypersensitivities (i.e.: allergies). It can be difficult to differentiate between a dry and an allergic eye. In these cases, HYLO-DUAL® is advantageous thanks to the dual mode of action of Sodium Hyaluronate and Ectoine.

Together, Sodium Hyaluronate and Ectoine provide intensive long-lasting lubrication of the ocular surface and protect against the evaporation of tears to relieve itching and burning caused by inflammation and allergies.

References: Galinski, E.A. et al. Eur J Biochem 1985; 149: 135); Brown, A. D. et al. Advances in Microbial Physiology 1978; 17: 181; Lippert, K. and Galinski, E.A., Appl Microbiol Biotechnol 1992; 37:61-65; Brünger, J. et al. IFSCC Magazine 2001; 4: 1; Galinski, E.A. et al. Comp Biochem Physiol 1997; 117A: 357; Graf, R. et al. Clinics in Dermatology 2008 26, 326-333; Brünger, J. and Driller, H., Skin Pharmacol Physiol 2004; 17:232-237; Harishchandra, R.K. et al. Biophys. Chem 2010, doi:10.1016/j.bpc.2010.02.007; Dwivedi, M. et al. Part A: Natural meibomian lipid films, Biochim. Biophys. Acta (2014), http://dx.doi.org/10.1016/j.bbamem.20..., Part B: Artificial lipid films, Biochim. Biophys. Acta (2014), http://dx.doi.org/10.1016/j.bbamem.20... data on file