Clostridium difficile: Epidemiology, Guidelines, and Laboratory Diagnosis- All in a State of Flux

Fred Tenover, Ph.D. (D)ABMM, Executive Director for Scientific Affairs, Cepheid, gives a presentation at Xpert Club U.K. 2010.  #Cdifficile, #Cdiff

0:00 Introduction
2:20 Clostridium difficile - the Organism
4:44 Changing Epidemiology of Clostridium difficile Infection
11:16 Ribotype 027 Epidemic Strain of C. difficile
24:12 Environmental Control Issues What is on that keyboard? Detecting hidden environmental reservoirs of Clostridium difficile during an outbreak associated with North American pulsed-field gel electrophoresis type strains. (0271BI NAP1)
33:32 What is the gold standard for testing?
34:59 Molecular Amplification Tests for Clostridium difficile detection
36:30 Comparison of Molecular Methods for C. difficile
38:44 CDI Detection: 1000 patients, 10% prevalence
44:58 GDH versus PCR Reconsidered
48:08 Dr. Dale Gerding's Predictions for C. difficile Epidemiology