Learn MMP-12 in 3 minutes | Matrix metallopeptidase 12

This is an introductory video about MMP-12 (aka matrix metallopeptidase 12, macrophage metalloelastase, or macrophage elastase), intended for scientists who need to design controls and perform immunoassays detecting MMP-12. It contains information about western blot band size, protein expression, and interesting facts.

Uniprot: https://www.uniprot.org/uniprot/P39900
Human Protein Atlas: https://www.proteinatlas.org/ENSG0000...
Western blot images on PMC: https://www.ncbi.nlm.nih.gov/pmc?term...

MMP-12 Antibodies
Anti-Macrophage Metalloelastase MMP12 Antibody (RP1089): https://www.bosterbio.com/anti-mmp12-...
Anti-Macrophage Metalloelastase MMP12 Antibody (PA2146): https://www.bosterbio.com/anti-mmp12-...
Anti-MMP12 Rabbit Monoclonal Antibody (M01520): https://www.bosterbio.com/anti-mmp12-...

MMP-12 ELISA Kits
Human MMP-12 ELISA Kit PicoKine™ (EK0950): https://www.bosterbio.com/human-mmp-1...
Mouse MMP-12 ELISA Kit PicoKine™ (EK0996):
https://www.bosterbio.com/mouse-mmp-1...

Learn more about MMP-12 (infographic and discussion): https://www.bosterbio.com/bosterbio-g...

Boster Biological Technology
Website: www.bosterbio.com
Email: [email protected]

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REFERENCES

Cabral-Pacheco, G. A., Garza-Veloz, I., Castruita-De la Rosa, C., Ramirez-Acuña, J. M., Perez-Romero, B. A., Guerrero-Rodriguez, J. F., Martinez-Avila, N., & Martinez-Fierro, M. L. (2020). The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases. International journal of molecular sciences, 21(24), 9739.
https://doi.org/10.3390/ijms21249739

Iyer, R. P., Patterson, N. L., Fields, G. B., & Lindsey, M. L. (2012). The history of matrix metalloproteinases: milestones, myths, and misperceptions. American journal of physiology. Heart and circulatory physiology, 303(8), H919–H930. https://doi.org/10.1152/ajpheart.0057...

Ra, H. J., & Parks, W. C. (2007). Control of matrix metalloproteinase catalytic activity. Matrix biology : journal of the International Society for Matrix Biology, 26(8), 587–596. https://doi.org/10.1016/j.matbio.2007...

Zheng, T., Zhu, Z., Wang, Z., Homer, R. J., Ma, B., Riese, R. J., Jr, Chapman, H. A., Jr, Shapiro, S. D., & Elias, J. A. (2000). Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. The Journal of clinical investigation, 106(9), 1081–1093.
https://doi.org/10.1172/JCI10458