Скачать или смотреть Podcast 144: Hip fractures, PPIs, and smoking history in postmenopausal women — increased risks

PPIs are back on our radar, and this time it’s their regular use among postmenopausal women.



A BMJ article examines data from the Nurses’ Health Study to show a significantly increased risk for hip fracture among postmenopausal women with any smoking history. Never-smokers showed no statistically significant increase.



Now that proton pump inhibitors have been available over-the-counter for the better part of a decade, should clinicians be asking about their patients’ smoking history in concert with asking about how they handle heartburn?



Links:



BMJ article (http://www.bmj.com/cgi/doi/10.1136/bm...) (free)



Physician’s First Watch summary (http://firstwatch.jwatch.org/cgi/cont...) (free)



FDA’s May 2010 warning on PPIs and fracture risks (firstwatch.jwatch.org/cgi/content/full/2010/526/3) (free)



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