ACTION POTENTIALS IN NEUROPHYSIOLOGY by Professor Fink

Review of the Generation & Conduction of Action Potentials. This Lecture reviews the opening & closing of Ion Channels, the Relationship between Stimulus Intensity & Response, the Relationship between the Electrical Refractory Period & Frequency of Action Potentials, and the Factors affecting Conduction Velocity (Diameter of Fiber & Myelination). Reference is made to concentration gradients, electrical gradients, ligand-gated Na Channels, voltage-gated K Channels, voltage-gated Na Channels, electrical polarity, depolarization, repolarization, hyperpolarization, Na/K-ATP Pumps, Subthreshold Stimulus, Local Response, Threshold Potential, Suprathreshold Stimulus, myelinating cells (oligodendroglia & Schwann cells), Nodes of Ranvier, Saltatory Conduction, Multiple Sclerosis and fibrosis.

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