Cori Cycle | Lactic acid Metabolism | Glucose-Lactate Cycle | Importance of Cori Cycle | Metabolism

This video provides a tutorial on Cori Cycle or Lactic Acid Fermentation. Cori cycle occurs takes place in skeletal muscle and liver and also in cells which lack mitochondria such as red blood cells. During intense exercise, oxygen may not reach the muscle cells fast enough to keep up with the workout. This triggers the anaerobic glycolysis in skeletal muscles and coverts pyruvate to lactate. Lactate is then transported to liver, where it is recycled back to glucose through gluconeogenesis. Glucose is then transported to skeletal muscle, wherein it is then stored as glycogen or used up to generate energy int eh form of ATP through glycolysis. Cori cycle consumes 6 molecules of ATP. It also prevents lactic acidosis in skeletal muscle.
The following topics are covered in this lesson,

1. Cori cycle
2. Lactic acid fermentation
3. Lactic acidosis
4. Anaerobic metabolism
5. Glucose lactate cycle
6. Aerobic metabolism
7. Gluconeogenesis
8. Glucose-6-phosphatase
9. Fructose-6-phosphatase
10. Glycogenolysis