The Paradox of Immunity

Air date: Wednesday, March 10, 2010, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Category: Wednesday Afternoon Lectures
Description: Following postdoctoral studies at the NIH with Dr. Phil Leder, where he identified and characterized the genes for the human IgM antibody and the DNA elements involved in switch recombination, in 1982 Dr. Ravetch joined the faculty of Memorial Sloan-Kettering Cancer Center and Cornell Medical College. His laboratory cloned the first genes for Fc receptors, identified the SHIP inhibitory receptor signaling pathway and contributed significantly to understanding the mechanisms of antibody mediated effector responses, establishing the FcR pathways as fundamental components of the immune response. In addition to his studies on antibody receptors, Dr. Ravetch has made fundamental contributions to the genetics of the malaria parasite and with the identification of the first chemokine, IP-10, established this class of molecules as novel mediators of inflammation. He returned to The Rockefeller University in 1996 to establish the Laboratory of Molecular Genetics and Immunology.

The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Author: Dr. Jeffrey Ravetch
Runtime: 01:16:59
Permanent link: http://videocast.nih.gov/launch.asp?1...