An Air- and Moisture-stable Ruthenium Catalyst for Diverse Reactivity with Gillian McArthur

In this Research Spotlight episode, Gillian McArthur (Larrosa group, University of Manchester) joins us to share her work on the development of an air- and moisture-stable ruthenium catalyst for diverse reactivity.

Key reference:
https://doi.org/10.1038/s41557-024-01...

This episode has an associated problem set, available for download synthesis-workshop.com

Additional references (in order of appearance):
Examples of applications: Frost et al. Chem. Soc. Rev. 2017, 46, 7145-7153. Larrosa et al. Nature Chem. 2018, 10, 724-731.
Conditions adapted from Larrosa et al. Nature Chem. 2018, 10, 724-731. Larrosa et al. Chem 2020, 11, 1459-1468.
Conditions adapted from Larrosa et al. Chem Catal. 2021, 1, 691-703. Larrosa et al. JACS Au 2022, 2, 2529-2538.
Conditions adapted from: Ackermann et al. Angew. Chem. Int. Ed. 2019, 58, 9820-9825. Ackermann et al. Chem Sci. 2021, 12, 8073-8078.
Conditions adapted from: Li et al. J. Org. Chem. 2020, 85, 2242-2249.
Conditions adapted from: Leyva-Pérez et al. Nature Communications, 2022, 13, 2831-2840. Petit et al, Adv. Synth. Catal. 2013, 355, 2584-2590.
Conditions adapted from: Zhang et al. J. Org. Chem. 2001, 66, 4814–4818.
Conditions adapted from: Sigman et al. J. Am. Chem. Soc. 2017, 139, 9503-9506.
Conditions adapted rom: Zhang et al. J. Org. Chem. 2001, 66, 4814–4818.
Conditions adapted from: Leonori et al. Science 2020, 367, 1021-1026.