Keto os experts bring you information on the history of ketones and ketosis in episode 4 of Keto 101.
Our mission is to show you that anyone can bio-hack their own body, and we can Prüvit. However, to do this effectively requires knowledge, technology, self experimentation and most importantly, the willingness to question everything you’ve ever believed to be true about nutrition.
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FULL TRANSCRIPT
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What do you know about the history of
ketones dating back to when did we even
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discover that our bodies from making
ketones?
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Ever since humans were around
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ever since animals existed you know
ketones existed.
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If you think of our
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hunter-gatherer past the hunting was not
always good and the gathering was not
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always good and these people would go
into ketosis and then they would kill an
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animal perhaps and there was no
refrigeration so the little group ate
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the whole thing and that would probably
knock them out of ketosis. Now this was
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known for a long time but the mechanism
wasn't known but they knew that
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starvation worked and that was because
of course that starvation was elevating
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the ketones probably most likely
acetoacetate was the ketone having that
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function.
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And around 1921 it was
discovered that if someone ate a
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extremely high fat diet like 80 to 90
percent of the calories as fat and
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greatly reduced the carbohydrate that
that would mimic starvation and they
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discovered shortly after that that it
was actually an elevation of ketones
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that was a big factor in this.
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In the late 1920s Johns Hopkins University
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developed a ketogenic diet.
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There was one researcher who noticed
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when he took a vigorous walk in the
morning for some reason he started
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measuring ketones in his urine they
started calling it post exercise ketosis
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and there were a lot of studies in the
1930s of that and it was shown in the
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1960s then that during starvation like
as you start over a number of days that
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the ketone level would increase from
virtually zero you know before they
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started this fast to get quite high over
a period of about
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10 to 12 days or so and then kind of
level off and as long as you have fat to
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burn you will keep making ketones and
your ketone levels will stay up at that level.
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The very first ester was like drinking rocket fuel.
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It tasted really bad.
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I've never drank
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rocket fuel I mean I worked at NASA but
everything took a sip but I'm this was
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the most awful thing and they were
making it and like white barrel like
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pails. I brought a pharmacologist with me
and works for the department she went
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drinking so I took her bottle with me so
I just seems like rocket fuel up i'm taking it.
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So we're just starting our research now
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so we're just on a research and looking
at the impact of exogenous ketones
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on things like creating low levels of
oxygen and performance deficits that
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happen in that setting. We're looking at
it for cold water divers and being able
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to protect against hypothermia.
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More than 20 years later we actually have an
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exogenous ketone that you know people
can simply take and increase their
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ketone levels and experience the
benefits.
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It's the last three years that
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have blown up the whole industry now a
bunch of young scientists are studying
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research is doubling tripling
quadrupling why, cause honestly the Prüvit
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community is going out there and telling
everybody around the world just how
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powerful this message is and it's
changing the game.
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