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Finally got a nice sub 2:50 kill. You can go faster but would need to tweak the rotations a bit. Slowest part is probably the dogs and could change p4 slightly.

Familiar: Ripper Demon, autofire: 1s
Consumables: Lantadyme sticks, spiritweed sticks
Aura: Equilibrium
Passive: Ring of vigour, infernal box, reaper crew
Relics: COE, FOTS, font of life
t95 Top: Biting 4 + Undead slayer, C4R5
t95 Bottoms: Imp 4 + Devo 4, Invig 4 + mobile
t100 Omniguard: P6AS1(genesis upgrade)
t100 Soulbound lantern: AS4E2(genesis upgrade)
t100 Soulbound lantern(barrows): Flanking 4
EOF: Deathguard
Ring: Occultist
Pocket slot: Ful book