Motrin IB (Ibuprofen) – Side Effects, Uses, Mechanism of Action, Dosage, Interactions, Warnings

Motrin IB (Ibuprofen) – Side Effects, Uses, Mechanism of Action, Dosage, Interactions, Warnings
Motrin IB, a brand name for ibuprofen, is an NSAID used to relieve mild to moderate pain, reduce fever, and alleviate inflammation and swelling. Common side effects include upset stomach, nausea, vomiting, headache, dizziness, and drowsiness, while serious side effects can involve stomach bleeding, heart attack, stroke, high blood pressure, kidney problems, and severe allergic reactions. Adults and children over 12 should take 200 to 400 mg every 4 to 6 hours as needed, not exceeding 1200 mg in 24 hours unless advised by a doctor. Ibuprofen works by inhibiting COX-1 and COX-2 enzymes, reducing the production of prostaglandins, thereby lessening inflammation, pain, and fever. Interactions with anticoagulants, antihypertensives, other NSAIDs, methotrexate, and lithium can increase the risk of serious side effects. Warnings include significant gastrointestinal risks and the need to avoid use during pregnancy, especially in the third trimester.
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