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Dr. Todd and Allycia react to Episode 2 of Cells at Work! (“Scrape Wound”) and break down what actually happens in the body during a skin abrasion.

We explain how platelets rapidly clump to stop bleeding, how a platelet plug and fibrin clot form, and why closing a wound prevents bacteria from entering.
The episode’s microbes—Staph aureus, Group A strep, and Pseudomonas—lead into a discussion of neutrophils as first-line defenders and how white blood cells coordinate the immune response.

Dr. Todd covers key hematology and immune concepts, including:
-CBC with differential and what each white blood cell does
-Primary vs secondary hemostasis
-Von Willebrand disease vs hemophilia and why bleeding patterns differ
-Platelet count vs function when evaluating bleeding

We also discuss where platelets come from (megakaryocytes), the roles of thrombopoietin vs erythropoietin, and why liver disease, kidney disease, or bone marrow disorders can affect blood counts. Allycia shares her experience with gestational thrombocytopenia, along with real-world platelet thresholds, ITP, and transfusion considerations.

We wrap up with a preview of the next episode (“Influenza”) and a teaser for upcoming discussions on vaccines and viral evolution.

🧬 Educational content provided by a licensed physician for informational purposes only. This does not replace medical advice.

⏱️ Chapters
00:00 Intro
00:51 Reaction to CaW 1x2
03:26 Clot Formation: Fibrin & Platelet Plug
05:29 Bacteria Invade: Staph, Strep & Pseudomonas
08:11 Immune Cell Communication (Cytokines)
10:24 vWF & Sealing the Wound
13:48 Outro-Deep Dive
14:25 CBC w/ Diff: White Blood Cells Explained
16:46 Hemostasis Basics: Platelets & Clotting
19:29 Bleeding Disorders, Pregnancy & ITP
21:19 Influenza Preview & Vaccines Tease

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