53 Year Old Skin Cells Rejuvenated To 23 | Review By Modern Healthspan

In this video we talk about a study that used the Yamanaka factors to rejuvenate skin fibroblasts by 30 years. To do this they reprogrammed the cell into the maturation phase, where it had partly changed into a stem cell, yet still remembered its identity. When the Yamanaka factors were removed the cell went back to its original identity (a skin cell) but was now 30 years younger.

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Papers mentioned in the video:
Multi-omic rejuvenation of human cells by maturation phase transient reprogramming
https://elifesciences.org/articles/71624

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#yamanakafactors #reprogramming #rejuvenation