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Video Transcript;
What’s the best delivery system for CBD?
Is it really chewing gum and mints?
Let’s first look at a study of Pharmacokinetics of an orally delivered (ingested) CBD capsule formulation assessed in humans.
This information comes from [Hawksworth, G. and K. McArdle, Metabolism and pharmacokinetics of cannabinoids. The Medicinal Uses of Cannabis and Cannabinoids. Pharmaceutical Press, London, 2004: pages. 205-228.]
First; we must understand that the absorption of CBD from the gastrointestinal tract is erratic, resulting in a variable pharmacokinetic profile …
Then the study showed that bioavailability from oral delivery (capsules) was estimated to be 6% due to significant first-pass metabolism – [note that CBD gummies and beverages are similar]
So here is the net result of swallowing a 25mg CBD soft-gel capsule:
First; It was found that,, delivery of less than a staggering 2.5mg CBD was available for the body to use…
Therefore the relative cost to consumer is 10 times for bioavailable CBD…
That means a bottle of CBD capsules selling for $60 has an effective price of $600… Ouch
This next study has to do with Chewing gum with infused Caffeine
We will take a look at “The Rate of Absorption and Relative Bioavailability of Caffeine Administered in Chewing Gum Versus Capsules to Normal Healthy Volunteers.”
This information comes from a publication by [Kamimori, et al, International Journal of Pharmaceutics, 234 (1), p.159-167, March 2002]
They found that caffeine (100mg) in a chewing gum was absorbed at a significantly faster rate (five times) with bioavailability comparable to ingested caffeine capsules of over 80%...
Chewing gum is a convenient and effective means of rapidly administering caffeine as shown for military and exercise activities ,,,
This same study could apply to CBD in chewing gum
So what does all this have to do with CBD and the delivery of its medicinal benefits?
.
Well,,, how you consume the product can affect how potent it is,, and how easy it is to take.
Did you know that Over 40% of American Adults Report Experiencing Difficulty Swallowing Pills?,,
Once again this information comes from a [Harris Interactive National Survey and Schwarz Pharma, 2004]
The fact is,,, many people failed to take medication because of swallowing difficulties,,,
And most people have no problems swallowing food or liquid which results in these,,, medical implications which are that 14% delayed taking doses of their medication, 8% skip doses and 4% discontinued using their medication …that seems to be quite alarming.
We found that people are seeking alternative forms of the consumption of medication versus pills and capsules:
Why? One, For the ability to easily transport medications, – gum and mints travel well ,,,
Two,, The ease of administration, – gum and mints are easy to use,,,
Three, they require literally no preparation because, gum and mints are ready from the pack,,,
And, there is no need for water such as when you have to swallow pills, – no water for gum and mints,,,
Finally better taste, – gums and mints have a great taste!
Our Product are Consumer friendly,, – convenient and discrete,,, – as well as socially acceptable
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