Скачать или смотреть Differential Impacts on Reward Circuitry: Abuse Versus Psychedelics

Differential Impacts on Reward Circuitry: Abuse Versus Psychedelics

In what fundamental ways do drugs of abuse and psychedelics interact differently with the mesolimbic dopamine system and broader plasticity mechanisms?

Episode [121]: Detailed examination with Gül Dölen on how addictive substances create tolerance and dependence by overstimulating narrow reward pathways, while psychedelics—through serotonin 2A receptor agonism and critical period reopening—facilitate expansive, pro-social learning and sustained behavioral flexibility without reinforcing addiction-like patterns.

Not medical advice. Post questions in the comments.

Go to the Mind & Matter page for full episode:    / @mindandmatter  

#Psychedelics #Neuroscience #Addiction #RewardSystem #BrainPlasticity #Dopamine #MentalHealthResearch #SciencePodcast #MindAndMatterPodcast #NickJikomes #GülDölen