Скачать или смотреть Lecture on Electrolyte Biochemistry: Sodium, Potassium & Magnesium | MBBS | TSMC

[Intro Section] In this comprehensive biochemistry session, Dr. Portia Dewan from Tripura Santiniketan Medical College (TSMC) provides an in-depth analysis of major electrolytes—Sodium (Na+), Potassium (K+), Magnesium (Mg++), and Chloride (Cl-). This lecture is essential for MBBS students to master the physiological roles, diagnostic ranges, and clinical manifestations of electrolyte imbalances.

[Key Learning Objectives]

Sodium (Na+) Homeostasis: Understanding the chief ECF cation, RDA for hypertensives, and the mechanics of the Sodium-Potassium ATPase Pump [03:02].

Clinical Sodium Disorders: A deep dive into Hyponatremia and Hypernatremia, including life-threatening levels and the risks of rapid correction [08:42].

Potassium (K+) & Cardiac Health: Identifying ECG hallmarks like T-wave inversion in Hypokalemia and Peaked T-waves in Hyperkalemia [15:51].

Magnesium (Mg++) & Muscle Activity: The role of Magnesium as a cofactor in glycolysis and its impact on neuromuscular excitability [21:22].

Chloride Shift (Hamburger Phenomenon): A detailed recap of how chloride ions maintain acid-base balance and gas transport in erythrocytes [27:21].

[Interactive Timestamps] 00:00:00 - Introduction to Sodium (Chief ECF Cation) 00:01:11 - Recommended Dietary Allowance (RDA) & Reference Ranges 00:03:02 - The Sodium-Potassium ATPase Pump Explained 00:04:44 - Biochemical Functions: Osmotic Pressure & Heart Beat 00:06:11 - Resting Membrane Potential (RMP) & Action Potential 00:08:42 - Clinical: Hyponatremia (Causes & Symptoms) 00:11:13 - Treatment Protocols for Sodium Imbalance 00:11:59 - Hypernatremia: Causes like Diabetes Insipidus 00:13:23 - Potassium (K+): Major Intracellular Cation 00:15:37 - Clinical: Hypokalemia & ECG Finding (T-wave Inversion) 00:17:56 - Hyperkalemia: ECG Finding (Elevated T-wave) & DKA 00:20:52 - Pseudo-Hyperkalemia: Common Causes (Hemolysis) 00:21:22 - Magnesium (Mg++): Functions & RDA 00:23:42 - Hypermagnesemia vs. Hypomagnesemic Tetany 00:24:21 - Chloride (Cl-): Absorption & Homeostasis 00:27:21 - The Chloride Shift (Erythrocyte Physiology Recap)


TRIPURA SANTINIKETAN MEDICAL COLLEGE & HOSPITAL
Real time Classroom Demonstration/
BIOCHEMISTRY - LECTURE ON- SODIUM,
BY- DR. PORTIA DEWAN
(MBBS Batch: 2025-26)
Conducted on: 16-12-25