How Gluten Allergy can trigger Asthma? Which Flour asthmatic patients can substitute? Dr Amita Arora

Gluten allergy, often referred to as non-celiac gluten sensitivity or wheat allergy**, can sometimes trigger asthma symptoms in individuals who are predisposed to respiratory issues. Here's how gluten allergy can potentially lead to or exacerbate asthma:

Immune System Response
Gluten sensitivity or wheat allergy can cause an *overactive immune response*. When someone with a gluten allergy consumes gluten, their immune system reacts by releasing histamines and other inflammatory chemicals. This systemic inflammation can affect the lungs and airways, potentially triggering asthma symptoms.

Cross-Reactivity in Allergies
In individuals with wheat allergy (an IgE-mediated condition), exposure to gluten-containing products can provoke allergic reactions that might include bronchoconstriction (narrowing of airways), leading to asthma attacks.

Inflammation from Food Sensitivities
Gluten-related inflammation can sometimes increase the overall inflammatory load in the body. For individuals with asthma, this can worsen lung inflammation, reduce lung function, and make asthma symptoms more severe.

Gastroesophageal Reflux Disease (GERD) Connection
Gluten can trigger GERD in sensitive individuals, which can in turn worsen asthma. Acid reflux can irritate the airways, making them more prone to asthma attacks.

Microbiome and Gut-Lung Axis
Gluten intolerance or allergy can disrupt gut health, which is closely linked to lung health via the *gut-lung axis*. An imbalanced microbiome can lead to systemic inflammation, including in the lungs, thereby exacerbating asthma.

What to Do:
*Dietary Changes*: If gluten is suspected as a trigger, following a gluten-free diet might help alleviate symptoms.
*Consult Specialists*: Work with a dietitian and an allergist or pulmonologist to confirm gluten sensitivity and understand its role in asthma management.
*Manage Inflammation*: Anti-inflammatory medications or a carefully planned diet can reduce the overall inflammatory response.

If you experience asthma-like symptoms after consuming gluten, seek medical advice to rule out specific triggers and develop a tailored management plan.
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