Скачать или смотреть Microglia in Addiction & Early Career Development w/ Marcielo Martinez | Science at the Source Ep. 6

Welcome back to Science at the Source! 🎙️ In this episode, we sit down with Maricela Martinez, PhD student and rising star in neuroimmunology, to explore the groundbreaking connections between microglia, brain development, and addiction vulnerability.

Dr. Martinez and our host, Dr. Hilary Marusak, dive into:
• How microglia-the brain’s immune cells-shape neural circuits during adolescence, a critical period for addiction risk
• What happens when drugs of abuse like THC, nicotine, or opioids interact with microglia and alter brain development
• The concept of “innate immune memory” in microglia and how early drug exposure may prime the brain for later addiction
• The latest research on “resetting” microglia and its potential to reverse the long-term impacts of adolescent drug use
• Translational insights: How understanding microglia could lead to new strategies for preventing and treating substance use disorders

We also discuss the challenges and opportunities of pursuing research at the intersection of neuroscience and immunology as an early career scientist, and Dr. Martinez shares advice for trainees interested in this exciting field.
Don’t miss this engaging and thought-provoking episode featuring one of the brightest new voices in addiction neuroscience!
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Keywords: Microglia, addiction, adolescence, neurodevelopment, immune memory, brain circuits, drug exposure, THC, nicotine, opioids, substance use disorder, neuroimmunology, neuroscience careers, UC Irvine, Maricela Martinez, Science at the Source, Hilary Marusak