Скачать или смотреть Advances in Sub-cellular and Cellular in vivo Imaging for Systems Biology

LIVE WEBINAR: Dec 5, 2017
Sponsor: www.scintica.com

2:55 - Why is In Vivo microscopy important
8:18 - Overview of current In Vivo microscope technologies
17:24 - 3D image of visceral adipose tissue
25:26 - Explanation of miniaturized confocal microscopy
27:21 - The ViewnVivo system
28:23 - Illustrative examples of the ViewnVivo's capabilities
44:08 - Bundled fibre vs point scanning technology
47:26 - Where does whole body fluorescence imaging fit into the mix
48:50 - Comments on 3D image generation
51:07 - Comments on the laser technology of the ViewnVivo
55:04 - Comments on depth and dyes for ViewnVivo

Peter Delaney discusses unique combinations of advanced imaging instrumentation, fluorescent probes and key applications in terms of their capabilities, limitations and possibilities. Discussion centers on the importance of cellular and sub-cellular observations in vivo, often producing results counter to in vitro cellular behavior, and therefore streamlining research paths. In addition, he shares a variety of sample images, demonstrating novel capabilities in the world of high-resolution in vivo confocal endomicroscopic imaging.

Background:
In vivo fluorescence microscopy is advancing rapidly with the development of new imaging modalities and fluorescence labeling agents. It is now possible to image morphological, molecular, genetic, pathological and physiological events in the living animal. Laser scanning microscopes have advanced quickly, and even miniaturized confocal microscopes of endoscopic proportions can now create 3D observations at the cellular and sub-cellular level in vivo. This has led to a proliferation of techniques facilitating the transition of therapeutic research, bench-to-bedside, through direct in vivo observation of systems biologic processes.