Risk or benefit of removing ovaries at benign hysterectomy

An emulated target trial of more than 140,000 women in Denmark found that removing the ovaries at benign hysterectomy was associated with2increased risk for cardiovascular disease in younger women and cancer in older women at low risk for ovarian cancer. These findings support current recommendations for preserving ovaries in premenopausal patients.
Removal of the ovaries decreases the risk for ovarian cancer and greatly benefits the survival of women at high risk for ovarian cancer. However, not enough is known about how removal of the ovaries affects other possible outcomes, such as heart attack, stroke, other types of cancer, and how long patients live.


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