Скачать или смотреть Acetic Acid Fixative ; Definition, Properties, Mechanism, Application, Histology

Acetic acid is a commonly used fixative in histology and cytology, known for its ability to preserve cellular structures. Here's an overview:

Key Features:
Mechanism:

Acetic acid works by precipitating nucleoproteins and DNA, which helps preserve nuclear details.

It does not harden tissues, making it suitable for delicate specimens.

Applications:

Often used in combination with other fixatives (e.g., Carnoy's solution) to enhance fixation.

Commonly employed in cytology for preserving cells in smears.

Advantages:

Excellent for preserving nuclear morphology.

Rapid penetration and fixation.

Limitations:

Causes swelling of collagen and other proteins, which may distort tissue architecture.

Not ideal for preserving cytoplasmic details.

#AceticAcid #Fixative