Can I beat the hardest bosses in the game with Cursed Relic? [EXPERT/NO DAMAGE]

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My loadout:
CONTROLLER: Logitech Gamepad F310 - https://amzn.to/3dx2u8H
MICROPHONE: XLR Microphone, MAONO Cardioid Condenser Vocal Studio Recording Mic - https://amzn.to/3bU62kH
MONITORS: ASUS VL279HE 27” Eye Care Monitor - https://amzn.to/3pmWMsE