It is difficult to fit both William Zughbi’s and Huda Zughbi’s achievements on a page. Huda Zoghbi is Professor of Pediatrics, Molecular and Human Genetics, Neurology, and Neuroscience at Baylor College of Medicine. She is an Investigator with the Howard Hughes Medical Institute, and the founding Director of the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital. William A. Zoghbi is a renowned cardiology, echocardiography and cardiac imaging expert.
William Zoghbi has developed noninvasive heart function and valve disorder evaluation techniques, and went on to oversee national and international heart valve evaluation guideline development. He has implemented the American College of Cardiology ’s international mission and worked closely with its chapters around the globe. He has also represented the ACC and the global cardiovascular community at the United Nations and World Health Organization, advocating for a 25 percent reduction of the world’s noncommunicable disease mortality rate by 2025, known as the 25 x 25 Initiative.
He is the Chair of the Department of Cardiology at Houston Methodist Hospital, and holds the Elkins Family Distinguished Chair in Cardiology, established in his honor. In 2005, Dr. Zoghbi joined the Houston Methodist Specialty Physician Group following his 20-year tenure at Baylor College of Medicine, where he was the John S. Dunn Professor of Medicine and served as Houston Methodist’s echocardiography laboratory director. Dr. Zoghbi has authored more than 300 publications and has lectured at every major cardiology conference worldwide.
Huda Zoghbi’s work in neurodevelopment led to the discovery of the gene Math1/Atoh1 and to showing that it governs the development of several components of the proprioceptive, balance, hearing, vestibular, and breathing pathways. Huda’s group also discovered that mutations in MECP2 cause the postnatal neurological disorder Rett syndrome and revealed the importance of this gene for various neuropsychiatric features.
Huda trained over 100 scientists and physician-scientists and is a member of several professional organizations and boards. She has been elected to the National Academy of Medicine, the National Academy of Sciences, and the American Academy of Arts and Sciences. Among Huda’s honors are the Pearl Meister Greengard Prize from Rockefeller University, the Shaw Prize in Life Science and Medicine, the Breakthrough Prize in Life Sciences, Canada Gairdner International Prize, and Honorary degrees from Yale University, Harvard University and the University of Massachusetts Medical School, the Victor A. McKusick Leadership Award, American Society of Human Genetics, and the 2020 Brain Prize, Lundbeck Foundation and the Citation Laureate by Web of Science.
Huda values time with family and friends above all else. While she and William consider parenting Roula and Anthony as their greatest achievements, they are now having the most fun being grandparents to Camila, Tate, and Sienna. The couple’s individual contributions to the medical community and research have crossed borders, and will probably continue to do so for decades to come.
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