Pharmacology – ANTIBIOTICS – CELL WALL & MEMBRANE INHIBITORS (MADE EASY)

👉📖 READY TO ACE YOUR EXAM? 📚 GET STUDY NOTES ON PATREON!
  / speedpharmacology  

Antibiotics, also known as antibacterials, are a group of drugs used to treat various infections caused by bacteria. Antibiotics work by either selectively killing (bactericidal) or inhibiting the growth (bacteriostatic) of bacteria. This pharmacology lecture covers topics such as classification of antibiotics; cell wall structure of Gram-negative bacteria, Gram-positive bacteria, Mycobacteria; mechanism of action and side effects of Cell Wall Synthesis Inhibitors: Beta-lactams (Penicillins, Cephalosporins, Carbapenems, Monobactams), Beta-lactamases (Avibactam, Clavulanic acid, Sulbactam, Tazobactam), Fosfomycin, Cycloserine, Vancomycin, Bacitracin, Antimycobacterial drugs (Isoniazid, Ethambutol), mechanism of action and side effects of Cell Membrane Integrity Disruptors: Daptomycin, Polymyxins.

Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!!

Source of diagram depicting the enzymatic steps involved in S. aureus cell wall synthesis: http://www.biomedcentral.com/1471-218...

0:00 Intro
2:02 Bacterial cell wall structure
3:02 Beta-lactams & Beta-lactamases
6:18 Enzymatic steps of cell wall synthesis
8:24 Fosfomycin, Cycloserine, Vancomycin, Bacitracin
11:38 Mycobacterial cell wall inhibitors
14:24 Cell membrane integrity disruptors