19. Pseudohyperkalemia in horses with rhabdomyolysis reported by an enzymatic chemistry analyzer

Pseudohyperkalemia in horses with rhabdomyolysis reported by an enzymatic chemistry analyzer

https://pubmed.ncbi.nlm.nih.gov/38103...

1. What is the main objective of the study described in the source?
A. To investigate the prevalence of rhabdomyolysis in horses.
B. To compare the accuracy of different blood chemistry analyzers in horses with rhabdomyolysis.
C. To determine the most effective treatment for hyperkalemia in horses with rhabdomyolysis.
D. To evaluate the relationship between serum creatine kinase activity and serum potassium levels in horses with rhabdomyolysis.

2. What is the primary reason for the VetScan VS2 analyzer reporting falsely elevated potassium concentrations in horses with rhabdomyolysis?
A. The analyzer uses an ion-specific electrode that is sensitive to interference from myoglobin.
B. The analyzer's methodology involves a coupled-enzyme reaction utilizing lactate dehydrogenase, which is elevated in rhabdomyolysis.
C. The analyzer is not properly calibrated for use in equine patients.
D. The analyzer is prone to error when measuring potassium levels in samples with high creatine kinase activity.

3. What alternative analyzers are recommended for evaluating serum potassium concentrations in horses with rhabdomyolysis?
A. VetScan VS2 and Cobas
B. i-STAT Alinity Base Station, Catalyst, and Cobas
C. Only the VetScan VS2
D. None of the above

4. What is a potential consequence of pseudohyperkalemia in horses with rhabdomyolysis?
A. Unnecessary and expensive treatment for hyperkalemia.
B. Underestimation of the severity of the rhabdomyolysis.
C. Delayed diagnosis of the underlying cause of the rhabdomyolysis.
D. Increased risk of complications such as laminitis and colic.