Acyclovir 200mg ( Zovirax ): What is Acyclovir Used For, Dosage, Side Effects & Precautions?

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This is lesson n# 18 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Acyclovir 200mg ( Zovirax - Aciclovir ): What is Acyclovir Used For, Dosage, Side Effects & Precautions?

In 3 minutes you'll learn about:

What is Acyclovir ?
Acyclovir mechanism of action, uses, dosage, side effects, and precautions...
MORE DRUG INFO HERE:
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In this video we'll briefly discuss what is Acyclovir, how it works, what it's used for, the dose and side effects, contraindications and precautions.

Acyclovir is an antiviral active against herpes simplex virus and varicella zoster virus. It inhibits viral DNA replication by interfering with viral DNA polymerase.

It is available as 200 mg, 400 mg and 800 mg tablets, and as 40 mg/ml oral suspension. Also available for topical use and injection.

Acyclovir uses:

Treatment of recurrent or extensive oral and oesophageal herpes in immunocompromised patients.
Treatment of herpetic kerato-uveitis.
Treatment of genital herpes.
Secondary prophylaxis of herpes in patients with frequent and/or severe recurrences.
Treatment of severe forms of zoster: necrotic or extensive forms, facial or ophthalmic zoster.

Dosage of Acyclovir:

Treatment of recurrent or extensive oral and oesophageal herpes in immunocompromised patients, treatment of herpetic kerato-uveitis
Child under 2 years: 200 mg 5 times per day for 7 days
Child over 2 years and adult: 400 mg 5 times per day for 7 days
Treatment of genital herpes
Child over 2 years and adult: 400 mg 3 times per day for 7 days; in immunocompromised patients, continue treatment until clinical resolution
Secondary prophylaxis of herpes in patients with frequent and/or severe recurrences
Child under 2 years: 200 mg 2 times per day
Child over 2 years and adult: 400 mg 2 times per day
Treatment of severe forms of zoster
Adult: 800 mg 5 times per day for 7 days

And for topical use, for both adults and children: Apply to lesions every 3 hr, 6 times/day.

Contraindications:

Do not administer to patients with hypersensitivity to acyclovir.

Acyclovir side effects:

Acyclovir ( Zovirax ) may cause: headache, skin rash, allergic reactions, gastrointestinal disturbances, raised transaminases, neurologic disorders in patients with renal impairment and elderly patients; rarely, haematological disorders.: Reactions range from mild to life threatening.

Precautions:

Reduce dosage in patients with renal impairment.
Drink a lot of liquid during treatment.
Genital herpes: Sexual intercourse must be avoided when lesions are present. Use of acyclovir does not prevent transmission.
Pregnancy: no contra-indication
Breast-feeding: no contra-indication

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