Drugs for Asthma Treatment

This is a short video on drugs used to treat the obstructive airway disease asthma.

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ADDITIONAL TAGS:
Antigen/Irritant/Trigger
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
Sympathetic (β2-mediated) Bronchospasm
Mediators
DRUGS FOR ASTHMA

Antigen/Irritant/Trigger
Mediators
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Sympathetic (β2-mediated) Bronchospasm
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
β2-agonist
(albuterol)
long acting β2-agonist
(salmeterol, formoterol)
Muscarinic antagonist
(ipratropium,
tiotropium,
umeclidinium)
antibodies
(omalizumab for IgE,
mepolizumab for IL5)
Inhaled Corticosteroids (ICS)
PDE inhibitor (theophylline)
Leukotriene blockers
(zafirlukast, montelukast,
zileuton)

Antigen/Irritant/Trigger
Mediators
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Sympathetic (β2-mediated) Bronchospasm
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
β2-agonist
(albuterol)
long acting β2-agonist
(salmeterol, formoterol)
Muscarinic antagonist
(ipratropium,
tiotropium,
umeclidinium)
antibodies
(omalizumab for IgE,
mepolizumab for IL5)
Inhaled Corticosteroids (ICS)
PDE inhibitor (theophylline)
Leukotriene blockers
(zafirlukast, montelukast,
zileuton)

Antigen/Irritant/Trigger
Mediators
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Sympathetic (β2-mediated) Bronchospasm
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
β2-agonist
(albuterol)
long acting β2-agonist
(salmeterol, formoterol)
Muscarinic antagonist
(ipratropium,
tiotropium,
umeclidinium)
antibodies
(omalizumab for IgE,
mepolizumab for IL5)
Inhaled Corticosteroids (ICS)
PDE inhibitor (theophylline)
Leukotriene blockers
(zafirlukast, montelukast,
zileuton)

Antigen/Irritant/Trigger
Mediators
INFLAMMATION
-prolif/invasion of lymphocytes, eosinophils, macrophages, mast cells
-mediators (IgE, IL5, leukotrienes)
Sympathetic (β2-mediated) Bronchospasm
Reflex Parasympathetic Bronchospasm
mucus secretion, vasodilation, collagen deposition, alveolar remodeling, hyperplasia, etc
β2-agonist
(albuterol)
long acting β2-agonist
(salmeterol, formoterol)
Muscarinic antagonist
(ipratropium,
tiotropium,
umeclidinium)
antibodies
(omalizumab for IgE,
mepolizumab for IL5)
Inhaled Corticosteroids (ICS)
PDE inhibitor (theophylline)
Leukotriene blockers
(zafirlukast, montelukast,
zileuton)
short acting beta two agonist beta2 betatwo b2 btwo agonist short acting muscarinic cholinergic agonist