Decoded: Unlocking the Genetics Behind Life’s Clock

Welcome to this week's episode of Decoded!


Join us as we delve into the fascinating genetics behind aging and explore groundbreaking research that could help us turn back the clock. The episode is geared towards first-year undergraduate students to help them learn about research in the field of aging. 🧬✨


In this episode, we cover:

The biological process of aging and its impact on our bodies.

The role of genes and cellular aging, including discovering key genetic variants like AGE-1 and DAF-2.

Insights from studies on C. elegans and humans.

The latest research on gene length and its connection to aging.

Progeroid syndromes and their implications for understanding premature aging.

Latest advancements in reversing aging.


Whether you're curious about the genetics of aging or the cutting-edge technology aimed at extending our lifespans, this episode is packed with valuable insights and knowledge checkpoints to enhance your understanding. Don't miss out on this deep dive into the genetics of aging!


Voice Over: Charlie (elevenlabs.io)

Copyright: CC-BY-SA

Figures created with Biorender (https://BioRender.com) and Canva (https://www.canva.com/)


Research Articles:

Rare genetic coding variants associated with human longevity and protection against age-related diseases (https://www.nature.com/articles/s4358...)

Aging is associated with a systemic length-associated transcriptome imbalance (https://www.nature.com/articles/s4358...)

Remarkable longevity and stress resistance of nematode PI3K-null mutants (https://onlinelibrary.wiley.com/doi/1...)

Loss of epigenetic information as a cause of mammalian aging (https://www.cell.com/cell/fulltext/S0...)

Werner Syndrome - GeneReviews

(https://www.ncbi.nlm.nih.gov/books/NB...)