Could omega-3 prevent dementia? | Axel Montagne, Ph.D.

People with high levels of omega-3 DHA are ~50% less likely to develop Alzheimer's disease compared to people with low levels. Disruption of brain DHA transport via the MFSD2A transporter causes blood-brain barrier breakdown. Furthermore, where we lose pericytes - which are important for dementia prevention - overlaps with the loss of DHA transporters.

In this clip, Dr. Axel Montagne discusses how the brain transport of omega-3 DHA may be important for the prevention and possibly as a therapy for dementia.

Watch the full interview featuring Dr. Axel Montagne:
   • Axel Montagne, PhD, on Solving Alzhei...  

Timestamps:
00:00:00 - Introduction
00:00:30 - Loss of omega-3 transport
00:02:14 - Reduced glucose transport in brain
00:04:30 - Inhibition of VCAM1 (adhesion protein)
00:08:11 - Fibrinogen in the brain

Interview published on Feb 28, 2023

#Omega3 #Alzheimers #brain