Скачать или смотреть Bioinformatics Pairwise sequence alignment/pairwise2 in Biopython

#12daysofbiopython
In Day 3 of 12 days of Biopython video I am going to show you how to do global and local pairwise alignment between two different sequences with different matching scores and gap penalties. I am going to show you all different functions for alignment from pairwise2 and all different parameter combinations for scoring system and gap penalties.

Feel free to skip to chapter of your interest.
Chapters:
0:00 Intro
0:11 What is pairwise sequence alignment?
1:00 Global vs local pairwise alignments
1:29 Match score and gap penalty
1:51 Biopython pairwise2
2:36 Parameters for match scoring
3:14 Parameters for gap penalties
4:04 globalxx example - no gap penalty, default match scoring, 1 for matches, 0 mismatches
5:36 globalmx example - no gap penalty and custom match scoring
6:45 globalxs. example - default match scoring and custom get penalty for open gap and extended gap
7:40 globaldx example for protein alignment sequence using blosum62 matrix for scoring matches
8:25 globalmc example - defining function for gap penalties
9:37 Learn more about pairwise sequence alignments
9:54 Outro

You can find code/notebook connected to the topic here:
Github code:
https://github.com/lanacaldarevic/12-...

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