Скачать или смотреть Protein Model Quality - Part 3: Clustering AlphaFold's PAE in Jalview

This video explores how users can detect hidden domains in an AlphaFold structure using PAE cluster analysis in Jalview.

Video chapters include:
00:39 AlphaFold annotation in Jalview
01:46 Clustering AlphaFold's PAE
02:08 Cluster visualisation in 2D and 3D
03:06 Domain discovery

All online educational material was produced by Dr. Khadija Jabeen, School of Life Sciences, University of Dundee with support from Professor Geoffrey J. Barton, Dr. James Procter, Dr. Ben Soares, Renia Correya, Dr. Stuart MacGowan and Dr. Javier Sánchez Utgés. Funding from the Biotechnology and Biological Sciences Research Council (Grant number: BB/X018628/1) and the Wellcome Trust (Grant number: 218259Z/19/Z) is gratefully acknowledged.

Jalview can be downloaded at: https://www.jalview.org/download/

More information about Jalview's PAE score visualisation capabilities can be found at: https://www.jalview.org/help/html/fea...

Music: Smile from the mirror, Crowander, Free Music Archive, CC BY-NC 4.0.
https://creativecommons.org/licenses/...

(This work is licensed under the Creative Commons Attribution 4.0 International License)