Thermogelling Poly(N-isopropylacrylamide)-Graft-Chondroitin Sulfate Composites l Protocol Preview

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Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering - a 2 minute Preview of the Experimental Protocol

Thomas R. Christiani, Katelynn Toomer, Joseph Sheehan, Angelika Nitzl, Amanda Branda, Elizabeth England, Pamela Graney, Cristina Iftode, Andrea J. Vernengo
Rowan University, Department of Chemical Engineering; Rowan University, Department of Biological Sciences; Drexel University, Department of Biomedical Engineering;

An injectable tissue engineering scaffold composed of poly(N-isopropylacrylamide)-graft-chondroitin sulfate (PNIPAAm-g-CS)-containing alginate microparticles was prepared. The adhesive strength, swelling properties and in vitro biocompatibility are analyzed in this study. The characterization techniques developed here may be applicable to other thermogelling systems.

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