Скачать или смотреть NEET2026 MCQ: Pernicious Anaemia Explained | Most Expected RBC Maturation Question | EP-15 | 52 Days

EP - 15 | NEET 2026 Most Expected MCQ | 52 Days Left!

Question:
Anaemia due to failure of maturation of RBC is:
(a) Von Kluger’s disease
(b) Microcytic anaemia
(c) Normocytic anaemia
(d) Pernicious anaemia

Correct Answer: (d) Pernicious anaemia

Explanation:

Pernicious anaemia occurs when red blood cells fail to mature properly, most commonly due to a deficiency of vitamin B12.​

B12 is required for RBC DNA synthesis and cell maturation; low levels lead to large, immature, dysfunctional RBCs (megaloblastic anaemia).

Normocytic and microcytic anaemia have different causes and do not involve failed maturation due to B12 deficiency.

In exams, always connect deficiency of B12 with failure of RBC maturation and pernicious anaemia.​

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