Is Longevity Science Overhyped? | Professor Charles Brenner | The Proof Podcast EP

The desire to live longer is not new to humans. But as time goes on, the concept of extending lifespan seems to be less about fantasy and more about a scientific “cure”. In our rush to find a silver bullet, has science been subverted along the way?

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In Episode #272, Professor Charles Brenner joins me to answer this very question. There is immense opportunity for profit in the longevity and lifespan space, and therefore ample opportunity for misleading health claims and second-tier science. Dr Brenner brings his professional stance to the table in this conversation, offering his take on recent scientific developments and the big players in the aging conversation.

Specifically, we cover:
00:00 - Intro
03:54 - Do we have the genes to live beyond 120 years?
14:18 - The genetics of extreme longevity
18:26 - Longevity in the animal kingdom
31:22 - Why do we age, and the realities of extending lifespan
39:01 - How long can we live?
43:49 - NAD coenzymes and DNA repair
55:17 - "Anti-ageing" products
1:01:08 - Conflicts of interest and the integrity of scientific claims
1:03:19 - Discovering nicotinamide riboside (NR) (vitamin B3)
1:10:22 - Sirtuins as anti-ageing genes
1:20:05 - A rebuttal to Drs. David Sinclair and Lenny Guarente
1:33:28 - Seeking consensus on the study of human longevity
1:44:13 - The information theory of aging
2:04:25 - Dr. Charles Brenner's theory of ageing
2:05:30 - How to age better
2:07:25 - Dr. Brenner on the quality of life
2:11:05 - NR supplementation
2:17:46 - Moving beyond Yamanaka factors
2:19:40 - Outro

Connect with Dr Charles Brenner:
Twitter:   / charlesmbrenner  
Website: https://www.brennerlab.net/

If you have any additional questions you would like answered in the future, let me know in the comments.

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Enjoy, friends.
Simon

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