IVIS for Neuro-Invasive Encephalitic Virus : Imaging | Protocol Preview

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In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus - a 2 minute Preview of the Experimental Protocol

Allison Poussard, Michael Patterson, Katherine Taylor, Alexey Seregin, Jeanon Smith, Jennifer Smith, Milagros Salazar, Slobodan Paessler
University of Texas Medical Branch , Experimental Pathology;

Utilizing luciferase and in vivo imaging systems (IVIS) as a novel means to identify disease endpoints before clinical developments occur. IVIS has allowed us to visualize in real time the invasion of encephalitic viruses over multiple days, providing a more accurate disease model for future study. It has also allowed us to identify the potential protective features of antivirals and vaccines faster than currently utilized animal models. The capability to utilize individual animals over multiple time points ensures reduced animal requirements, costs, and overall morbidity to the animals utilized ensuring a more humane and more scientific means of disease study.

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