Agonista del receptor GLP 1: mecanismo de acción

Tópicos:
PC2 (procenvertasa 2) PC1 (proconvertasa 1)
PC3 (proconvertasa 3)
DPP4 (Dipeptidil peptidasa 4)
Ref:
Goodman & Gilman's: The Pharmacological Basis of Therapeutics, Thirteenth Edition

Cornell, S. (2020). A review of GLP‐1 receptor agonists in type 2 diabetes: A focus on the mechanism of action of once‐weekly agents. Journal of Clinical Pharmacy and Therapeutics, 45(S1), 17–27. doi:10.1111/jcpt.13230

Nauck, M. A., Quast, D. R., Wefers, J., & Meier, J. J. (2020). GLP-1 receptor agonists in the treatment of type 2 diabetes – state-of-the-art. Molecular Metabolism, 101102. doi:10.1016/j.molmet.2020.101102

Holst, J. J. (2007). The Physiology of Glucagon-like Peptide 1. Physiological Reviews, 87(4), 1409–1439. doi:10.1152/physrev.00034.2006

Griffith DA, Edmonds DJ, Fortin J-P, Kalgutkar AS, Kuzmiski JB, Loria PM, et al. A small-molecule oral agonist of the human glucagon-like peptide-1 receptor. J Med Chem [Internet]. 2022;65(12):8208–26. Disponible en: http://dx.doi.org/10.1021/acs.jmedche...

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