Beat SCAD Conference 2023 – Rapidly advancing SCAD research

Beat SCAD Conference, 14 October 2023: Spontaneous Coronary Artery Dissection – The Power of Patients and Research as a Driver for Change

Dr David Adlam, Professor of Acute and Interventional Cardiology, Department of Cardiovascular Sciences, University of Leicester, Cardiovascular Research Centre at Glenfield General Hospital, Leicester, discusses the recent genetics paper, other recent research and introducing the New Clinical Research Fellow, Dr Anju John, part-funded by Beat SCAD.

00:00:10 History of SCAD research in the UK
00:02:46 Collaboration is key
00:04:42 The first 10 years of research
00:06:33 What we have achieved
00:07:20 The first risk gene associated with SCAD (PHACTR1)
00:07:50 The first Cardiac MRI findings
00:08:04 The first gene sequencing in SCAD
00:09:15 Patient care and outcomes (Cardiac MRI study)
00:10:42 MRA study - Serious vascular events in SCAD patients are very rare
00:11:58 PCI paper - Conservative management is correct for most patients but some will need intervention (balloon angiography, stents, bypass grafts)
00:13:44 Diagnostic challenges and SCAD mimics
00:15:00 CTCA study - Developing a potentially non-invasive diagnostic test for SCAD
00:17:13 P-SCAD study
00:19:18 OCT study (what we think is happening in SCAD)
00:21:36 Pathology study looking at collogen fibres (connective tissue)
00:22:58 Genetics studies - Familial SCAD is very rare
00:25:38 GWAS (Genome-Wide Association Study) - International collaboration showed that 16 common genetic variants increase the risk of having a SCAD
00:33:08 Current and future research options
00:36:48 Introducing Dr Anju John, new Clinical Research Fellow (Feb 2024)
00:38:30 Dr Abi Al-Hussaini (London SCAD Clinic, Chelsea & Westminster)

See other videos from the Conference:
Beat SCAD – now we are 8, Rebecca Breslin    • Beat SCAD Conference 2023 – Charity a...  
SCAD in 2023 – What we now know, Dr David Adlam, lead UK SCAD researcher    • Beat SCAD Conference 2023 – What we n...  
What do we know about recovery from SCAD: Physical and mental health,
Professor Lis Neubeck    • Beat SCAD Conference 2023 – What do w...  
FMD – what SCAD patients need to know, Dr Tina Chrysochou,    • Beat SCAD Conference 2023 – Fibromusc...  
Q&A Session, Dr David Adlam, Prof Lis Neubeck, Dr Tina Chrysochou and Dr Anne Scott    • Beat SCAD Conference 2023 – Q&A session  
Beat SCAD Co-founder and Chair Trustee Rebecca Breslin concludes the Conference    • Beat SCAD Conference 2023 – Conferenc...  

And for more information about SCAD go to our website (beatscad.org.uk)