Скачать или смотреть Good news How you can grow natural teeth by taking one injection No need of dentist in 2030

Recent advancements in dental research have led to the development of innovative treatments aimed at regenerating human teeth through injectable methods.

Japanese pharmaceutical company Toregem Biopharma, in collaboration with Kyoto University, is developing an antibody drug that inhibits the USAG-1 protein, which suppresses tooth development. By blocking this protein, the drug activates dormant tooth buds, leading to the growth of new teeth. Successful trials in mice and ferrets have paved the way for human clinical trials, which began in October 2024. The initial focus is on patients with congenital tooth deficiencies, with the goal of making the treatment available by 2030.  

In another approach, researchers are exploring the use of injectable double-network (DN) hydrogels for dental pulp regeneration. These hydrogels mimic the extracellular matrix, providing a supportive environment for human dental pulp stem cells (hDPSCs). Studies have shown that DN hydrogels facilitate the differentiation and mineralization of hDPSCs, promoting the formation of pulp-like tissue both in vitro and in vivo. This method offers a minimally invasive strategy for regenerating dental pulp tissue. 

These developments represent significant strides in dental regenerative medicine, offering potential alternatives to traditional prosthetic treatments for tooth loss.