Скачать или смотреть Total Synthesis of Dragocins A−C through Electrochemical Cyclization (Baran, 2024)

An organic chemistry minilecture on the 'Total Synthesis of Dragocins A−C through Electrochemical Cyclization' by Brendyn P. Smith, Nathanyal J. Truax, Alexandros S. Pollatos, Michael Meanwell, Pranali Bedekar, Alberto F. Garrido-Castro, Phil S. Baran* It features an Electrochemical Oxidative Cyclization, an Barton-McCombie Chlorination and a divergent Moc carbamate reduction.




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References:
Angew. Chem. Int. Ed. 2024, e202401107 (this work)
Org. Lett. 2019, 21, 1, 266–27 (discovery)
Tet. Lett.1994, 35, 3099–3102 (AB3217-A synthesis)
J. Am. Chem.Soc. 1975, 97, 4264-4268 (Electrochemical Oxidation)
Chem. Rev. 2017, 117, 21, 13230–13319 (Electrochemical Oxidation Review)
Chem. Sci.,2017,8,8435–8442 (TPAP Oxidation)
Tet. Lett. 1983, 24, 4979–4982 (Barton-McCombie Chlorination)
Tetrahedron 2018, 74 , 4969e4979 (Barton-McCombie Mechanism(s))
J. Org. Chem. 1998, 63, 17, 5732–5733 (HOTT Barton-McCombie Reagent)