Скачать или смотреть Importance of DNA repair pathway in therapeutic combination strategies

Naoto Ueno, MD, PhD, University of Hawai’i Cancer Center, Honolulu, HI, discusses recent preclinical findings from human samples indicating the potential role of DNA repair pathways in the development of therapeutic combinations. While abnormalities in the DNA repair pathway did not emerge as predictive biomarkers for treatment outcomes, this does not rule out the possibility of effective drug combinations. Ongoing research, including studies using liquid and tumor biopsies, will aim to identify predictive biomarkers that may enhance treatment strategies. This interview took place at the European Society for Medical Oncology (ESMO) 2024 Congress in Barcelona, Spain.

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