Celecoxib Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses

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Celecoxib
Generic Name: celecoxib
Trade Name: Celebrex
Indication: osteoarthritis, rheumatoid arthritis, acute pain
Action: decreases pain and inflammation by inhibiting synthesis of prostaglandins
Therapeutic Class: antirrheumatics/NSAID
Pharmacologic Class: none
Nursing Considerations:
 use caution with cardiovascular disease
 increases risk for MI, CVA, thrombosis
 may cause GI bleeding, Stevens-Johnson syndrome, dermatitis
 notify provider for new-onset abdominal pain or black stool

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