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SOLUTIONS
Solution may be defined as a mixture of two or more components that form a single phase which is homogenous and clear.
solutions may be prepared from any combination of solid, liquid, and gas, the three states of matter. In pharmacy most of the solutions are prepared by dissolving a solid , liquid or gas in another liquid
It has two components:
Solvent
Solvent is the liquid portion of a solution in which another substance (e.g. salt) is dissolved to form a solution is called solvent.
Solute
A substance that is dissolved in another substance (solvent) to form a solution is called solute. Or
A solute is a substance that creates a solution when dissolved by a solvent. Solute can change its physical state, e.g. salt is solid before getting dissolved in water, and after dissolution it changes from solid to liquid.
Advantages:
1 They are homogenous, therefore the medicament is uniformly distributed.
2 They are more quickly effective than tablets or capsules because they are 3lready in solution form and absorption starts quickly.
4 They can easily colored, flavored and sweetened.
5 Children or patients who cannot swallow tablets or capsules can easily ingest solutions.
Disadvantages:
1 They are less stable as compared to solid dosage forms because deterioration is faster in solutions.
2 In some medicaments their unpleasant taste and flavor is difficult to mask.
Solubility :
The amount of substance that passes into solution in order to establish equilibrium at constant temperature and so produce a saturated solution is known as the solubility of the substance.
BP defined the solubility in an approximate manner that ‘the no of parts of solvent required to dissolve one part of solute”.
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